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Journal of Korean Society of Ultrasound in Medicine 1996 ; 15 (2) : p.331-338

Differentiation between Malignant and Benign Masses of Thyroid Gland Using Color Doppler Ultrasonogram
Chang Woo Son, M.D., Chang Woo Kim, M.D., Se Kwon Sin, M.D., Kyeung Jae Jang, M.D., Yi Tae KIm, M.D.1
Department of Diagnostic Radiology, Dae Dong Hospital Department of Diagnostic Radiology, Dong A Hospital
PURPOSE : To determine color Doppler ultrasound findings of malignant and benign thyroid nodules, and toidentify differential points among them. MATERIAL & METHODS : 35 patients with palpable enlarged thyroid noduleswere imaged by using with 7 MHz linear-array transducer. Color Doppler images were obtained in the transverse andlongitudinal planes on the color setting for the thyroid gland. After setting receiver gain, velocity scale andfilter were set to 6 cm / sec and 1, respectively. And we measured resistive index, pulsatility index, peaksystolic velocity and end diastolic velocity from the fastest or next fast arterial signals in the thyroid nodulesor in the margins of the thyroid nodules. Final diagnosis was confirmed by ultrasonography-guided or surgicalbiopsy. RESULTS : 25 cases of malignant nodule and 10 cases of benign nodule were confirmed histopathologically.On the color mapping, malignant nodules showed various internal flow signals from avascular to hypervascular andno marginal flow signals in all cases, and benign nodules revealed 9 (36%) hypovascular cases and 16 (64%)hypervascular cases in the internal flow signals and increased marginal flow signals in all cases. On the spectralanalysis, malignant nodules showed RI 0.7 (0.63∼0.83) in hypervascular internal flow signals and RI 0.93(0.67∼1.00) in hypovascular internal flow signals, and measured PI was 1.39 (1.03∼2.11), 2.71 (0.97∼4.81),respectively. and in benign nodules, measured RI was 0.65 (0.5∼0.88) and PI was 0.92 (0.59∼1.90). CONCLUSION :Color Doppler imaging can be helpful to differentiate benign and malignant thyroid masses by means of measuringmarginal and internal flow signals of thyroid nodules.
Keyword : Thyroid tumor. Ultrasonography, Thyroid tumor. Color Doppler Ultrasonography
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