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Journal of Korean Society of Ultrasound in Medicine 1993 ; 12 (2) : p.231-237

Breast papilloma and papillomatosis: the diagnostic roles of ultrasonography)
Suk Jong Ryu, M.D., Ki Keun Oh, M.D., Choon Sik Yoon, M.D., Woo Hee Jung, M.D., Chang Yoon Park, M.D.,
Department of Diagnostic Radiology, Yonsei University College of Medicine Department of Pathology, Yonsei University College of Medicine1
It is well known that the most common cause of nonlactational nipple discharge is intraductal papilloma orpapillomatosis. The diagnosis has been usually made by galactography. The presenting study is to evaluate the roleof ultrasonography in the diagnosis of papilloma and papillomatosis in comparison with galactography.Ultrasonograms and galactograms of 51 patients (34 with papilloma and 17 with papillomatosis) were analysed. Thesensitivity of each diagnostic modalitiy was calculated. On ultrasonography, main feature of papilloma wasintraductal mass with prominent dilatation of larger central duct. On the contrary, papillomatosis showed themasses that were related to the peripheral ducts in most patients. Dilatation of the peripheral ducts inpapillomatosis was mild. Similar features of intraductal filling defect (s) were seen in both papilloma andpapillomatosis. Galactography demonstrated the variable dilatation of the duct (s). Galactographic findings weresimilar to those of ultrasound in most cases. The sensitivity of ultrasound examination was 73.5% for papillomaand 76.5% for papillomatosis. The sensitivity of galactography was 82.4% for papilloma and 86.2% forpapillomatosis. The main advantage ultrasonography was its capability to demonstrate the lesion when the proximalduct was totally occluded on galactography. In conclusion, there was no significant difference in the sensitivitybetween ultrasound and galactography in the diagnosis of papilloma and papillomatosis. However, ultrasound wasbetter in demonstrating the nature and distal extent of the mass or masses.
Keyword : Breast neoplasms,US
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