|
| Ultrasound Elastography in Evaluation of Breast Lesions:
Phantom and Clinical Studies |
|
| Su Hyun Lee, MD1 Nariya Cho, MD1, Woo Kyung Moon, MD1,
Jung Chan Lee, PhD2, Jung Min Chang, MD1 |
|
| 1Department of Radiology, Seoul National University Hospital
2Institute of Medical and Biological Engineering, Medical Research Center, Seoul National
University |
|
| Purpose: The purpose of this study was to correlate the tissue stiffness measured
using ultrasound elastography with directly measured tissue stiffness.
Materials and Methods: A phantom model consisting of five materials with different
levels of stiffness was constructed. Forty one patients who were scheduled to
undergo a vacuum-assisted biopsy for breast lesions were prospectively recruited for
this study. Elasticity (E) score and strain index obtained with strain imaging were correlated
with the directly measured stiffness value of phantom and core specimen.
Results: The E score and strain index of each phantom material showed a high
level of correlation with the measured stiffness (E score: r = 0.985, P = 0.002; strain
index: r = 0.964, P = 0.008). The E score and strain index of the breast lesions
showed a low level of correlation with the reference standard (E score: r = 0.261, P =
0.100, strain index: r = 0.397, P = 0.014). The mean value of the E score was significantly
greater in malignant (3.6) than in benign lesions (2.4) (P = 0.004).
Conclusion: Stiffness of the phantom materials assessed by US strain imaging
was well correlated with the reference standard of direct measurement. The E score
can be used as a non-invasive diagnostic tool in differentiation of benign and malignant
breast lesions. |
|
| Keyword : Breast neoplasms; Ultrasound elastography; Tissue stiffness; Indentation test |
|
pdf파일 : 41-50이수현07.pdf 
|
|
> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2013 ; 32 (1) : p.41-50
