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| Risk of Lymph Node Metastasis in Papillary Thyroid
Microcarcinoma: Predictive Finding of Ultrasonography |
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| Hwa Seon Shin, MD1 Ji-hoon Kim, MD1, Dong Gyu Na, MD2 |
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| 1Department of Radiology, Seoul National University Hospital
2Department of Radiology, Human Medical Imaging and Intervention Center |
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| Purpose: The purpose of this study is to suggest predictive ultrasonographic finding
of papillary thyroid microcarcinoma (PTMC) with lymph node metastasis (LNM), compared
to PTMC without LNM.
Materials and Methods: This study included 93 patients (79 women, 14 men;
mean age 46.0 ± 10.6 years) with surgically proven PTMC. Twenty patients had
LNM and 73 patients did not have LNM on surgical specimens. The following ultrasonographic
characteristics were evaluated: tumor location, size, shape, echogenicity,
margin, presence of calcification, and presence of capsular abutment. Univariate
analysis and multivariable stepwise logistic regression analysis were performed for
comparison of these characteristics in regard to the presence of LNM in order to
determine predictors of LNM.
Results: Two factors were significantly related to LNM: presence of capsular abutment
(p = 0.0011) and tumor size (cutoff value: ≥ 5 mm, p = 0.0058). Lateral lymph
node metastasis (LLNM) showed a significant association with macrocalcification (p =
0.015), presence of capsular abutment (p = 0.0104), tumor size (cutoff value: ≥ 7
mm, p = 0.002), and upper location of thyroid nodule (p= 0.0255). Presence of capsular
abutment was an independent predictive factor for LNM (Odds ratio: 14.83, p =
0.010). Tumor size was an independent predictive factor for LLNM (Odds ratio: 2.102,
p = 0.010).
Conclusion: Presence of capsular abutment and tumor size are important ultrasonographic
predictors for LNM or LLNM in patients with PTMC. |
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| Keyword : Papillary thyroid microcarcinoma; Lymph node metastasis; Ultrasonography |
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pdf파일 : 33-39신화선02.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2013 ; 32 (1) : p.33-39
