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Contrast Enhanced US in the Abdomen |
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Yong Eun Chung, MD Ki Whang Kim, MD |
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Department of Radiology, Research Institute of Radiological Science, Severance Hospital,
Yonsei University College of Medicine, Seoul, Korea |
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Contrast enhanced ultrasound, which was introduced in 1996, has been widely
used in Europe and Eastern Asia. Ultrasound contrast agent can be classified as first
generation and second generation, depending on the gas within the microbubble.
With the first generation contrast agent, the high MI technique was used, and only
intermittent scanning was possible due to destruction of the microbubble during scanning.
Use of the second generation contrast agent with the low MI technique makes
continuous scanning possible. Contrast enhanced US can be used in detection and
differentiation of focal liver lesions. It is also helpful for monitoring of radiofrequency
ablation and for targeting of US guided biopsy. Currently, because morphologic criteria
alone may not reflect the response of the tumor to treatment, new criteria are needed
for treatment evaluation after administration of anti-angiogenic agents. Contrast
enhanced US could provide quantitative markers for evaluation of the response to
treatment via use of dynamic contrast enhanced US. Due to cost-effectiveness, contrast
enhanced US is not yet widely used in Korea; however, considering recent
issues regarding contrast agent related adverse reaction, such as contrast induced
nephropathy and nephrogenic systemic fibrosis, and radiation exposure, contrast
enhanced US might be more widely used in Korea, as an alternative imaging modality
in the future. |
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Keyword : Contrast enhanced ultrasound; Abdominal ultrasound; Liver |
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pdf파일 : 203-212정용은.pdf
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