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Role of Ultrasound Volume Measurements of Testes in
Evaluation of Infertile Men with Azoospermia |
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Min Hoan Moon, MD, PhD1 Ju Tae Seo, MD, PhD2, Yi Keong Chun, MD3,
Chang Kyu Sung, MD, PhD1, Jeong Yeon Cho, MD, PhD4,
Seung Hyup Kim, MD, PhD4 |
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1Department of Radiology, SMG-SNU Boramae Medical Center, Seoul National University
College of Medicine, Seoul, Korea
2Department of Urology, Cheil General Hospital & Women’s Healthcare Center, Kwandong
University College of Medicine, Seoul, Korea
3Department of Pathology, Cheil General Hospital & Women’s Healthcare Center, Kwandong
University College of Medicine, Seoul, Korea
4Department of Radiology, Seoul National University College of Medicine, and the Institute of
Radiation Medicine, Seoul, Korea |
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Purpose: The purpose of our study was to assess the usefulness of ultrasounddetermined
testicular volume in the evaluation of the infertile men with azoospermia.
Materials and Methods: A computerized search from October 2005 to June 2010
generated a list of 45 infertile men with azoospermia (mean age, 34 years; age range,
26-44 years) who underwent both scrotal ultrasound and testis biopsy. Ultrasounddetermined
testicular volumes were compared between infertile men with obstructive
azoospermia and those with non-obstructive azoospermia.
Results: Testicular volume for obstructive azoospermia ranged from 6.4 ml to 26.9
ml, with a median volume of 14.0 ml. This volume was significantly larger than that of
those with non-obstructive azoospermia, which ranged from 1.0 ml to 12.8 ml, with a
median volume of 6.1 ml (p < 0.001). The area under the ROC curve for distinguishing
non-obstructive azoospermia from obstructive azoospermia using testicular volume
was 0.91. A cutoff value of less than or equal to 11.4 ml could distinguish non-obstructive
azoospermia from obstructive azoospermia, with a sensitivity of 94.1% (95% CI;
71.3-99.9%) and a specificity of 73.3% (95% CI; 54.1-87.7%).
Conclusion: Ultrasound-determined testicular volume can be helpful in the differentiation
of obstructive azoospermia from non-obstructive azoospermia. |
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Keyword : Ultrasonography; Testis; Azoospermia |
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pdf파일 : 087-91문민환.pdf
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