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Underestimation of Ductal Carcinoma In situ on
Sonographically Guided Core Needle Biopsy of the Breast |
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Hye Doo Jung, MD1 Hyo Soon Lim, MD2, Se Hee Jung, MD1, Su Jin Jeong, MD2,
Hyun Ju Seon, MD1, Jin Woong Kim, MD2, Jung Han Yoon, MD3,
Jin Gyoon Park, MD1, Heoung Keun Kang, MD2 |
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1Department of Radiology, Chonnam National University Hospital
2Department of Radiology, Chonnam National University Hwasun Hospital
3Department of Surgery, Chonnam National University Hwasun Hospital |
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Purpose: The purpose of this study was to determine the underestimation rate of
ductal carcinoma in situ (DCIS) on sonographically guided 14-gauge core needle
biopsy of the breast and to investigate the factors associated with this underestimation.
Materials and Methods: We retrospectively reviewed 2990 consecutive lesions
that underwent sonographically guided 14-gauge core needle biopsy between
January 2005 and December 2008. Among them, 61 lesions were pathologically
proven to be DCIS (2.04%). A total of 50 DCIS lesions (mean patient age: 50.7 years
old, age range: 36-79 years old) that underwent surgical resection were included in
this study. After surgery, the lesion proven to be invasive was defined as being in the
underestimated group and the lesion proven to DCIS was defined as being in the correctly
diagnosed group. We determined the underestimation rate of DCIS and we retrospectively
reviewed and compared the clinical, pathologic and radiologic features of
the two groups.
Results: The underestimation rate of DCIS was found to be 28% (14 of 50 lesions).
The underestimation of DCIS was significantly frequent for a clinically palpable lesion
(78.6% (11/14) vs. 30.5% (11/36), respectively, p = 0.002). The sonographically maximal
diameter of a lesion was significantly larger in the underestimated group than that
in the accurately diagnosed group (28.4 ±14.0 mm vs. 17.6 ±10.3 mm, respectively,
p = 0.017) and underestimation was significantly frequent when the sonographic
lesion size was > 20 mm (p = 0.012). There was no significant difference in terms of
age, the lesion type, the Breast Imaging-Reporting and Data System (BI-RADS) category
or the pathologic features between the two groups.
Conclusion: The underestimation rate of DCIS was 28% for sonographically guided
14-gauge core needle biopsy of the breast. Clinical symptoms such as a palpable
lesion and a sonographic lesion size > 20 mm were the factors related with the underestimation
of DCIS. |
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Keyword : Biopsies, technology; Breast, biopsy; Breast, US; |
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pdf파일 : 133-139정혜두.pdf
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