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18F-Fluorodeoxyglucose Positron Emission Tomography
for Primary Thyroid Cancer: Correlation with the
Clinical, Pathologic and Sonographic Findings |
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Kyung-Eun Kim, MD Eun-Kyung Kim, MD, Hee Jung Moon, MD, Jin Young Kwak, MD |
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Department of Radiology, Yonsei University College of Medicine, Seoul, Korea |
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Purpose: We wanted to investigate the incidence and the clinicopathologic and
sonographic characteristics of thyroid cancers that exhibit positive PET scans.
Materials and Methods: From January 2007 to February 2008, 156 patients with
thyroid cancer underwent both sonography and FDG-PET for the purpose of staging
the cancer. We conducted a retrospective review of their clinical, radiologic and pathologic
records and we evaluated the incidence of PET-positive thyroid cancer, as well
as the associated clinicopathologic aggressiveness and the sonographic features.
Results: The incidence of PET-positive thyroid carcinoma was 78.2% (122/156).
On univariate analysis, PET-positive thyroid cancer was significantly associated with
tumor size, extracapsular invasion and central lymph node metastasis, but there was
no association between the sonographic features of the thyroid cancer or the sonographic
features of the 2 groups of tumor (1. probably benign and 2. suspicious for
malignancy) and the FDG uptake. Multivariate logistic regression analysis showed a
significant association between PET positivity and both extrathyroidal extension and a
higher cancer stage (III/IV) (p < 0.05).
Conclusion: The incidence of PET positive thyroid carcinoma is high (78.2%) and
PET positivity is significantly associated with tumor size, extracapsular extension and
a higher stage. However, there is no significant association between PET positivity
and the sonographic features of thyroid carcinoma. |
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Keyword : Thyroid; Positron emission tomography; Thyroid carcinoma |
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pdf파일 : 093-101김경은.pdf
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