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Usefulness of Ultrasound and Ultrasound-guided
Fine-Needle Aspiration Biopsy for Axillary Staging in
Breast Cancer: Analysis of 327 patients at a single
institution |
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Mijung Jang, MD Sun Mi Kim, MD, Chae-Yeon Lyou, MD,
Woo Kyung Moon, MD2, Nariya Cho, MD2, Eunyoung Kang, MD3
Sung-Won Kim, MD3, So Yeon Park, MD4, Jee-Hyun Kim, MD5, Yu Jung Kim, MD5 |
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1 Department of Radiology, Seoul National University Bundang Hospital
2 Department of Radiology, Seoul National University Hospital
3 Department of Surgery, Seoul National University Bundang Hospital
4 Department of Pathology, Seoul National University Bundang Hospital
5 Department of Medical Oncology, Seoul National University Bundang Hospital |
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aspiration biopsy (FNAB) for the diagnosis of metastasis in the axillary lymph node
(LN) of patients with breast cancer.
Materials and Methods: A retrospective review of the data was performed on 327
breast cancer patients that underwent axillary US from Jun 2006 to July 2008. USguided
FNAB was performed when a LN indicated suspicious findings. Results of
FNAB were compared with those of subsequent surgery.
Results: Of the 327 patients, 111 showed suspicious findings on US and underwent
FNAB. Among the 111 cases, 73 (66%) were positive for cancer, while 38 (34%)
were negative results. A Total of 254 patients who had normal findings on US
(n=216) and negative results on FNAB (n=38) underwent SNB, of which 56 (22%)
were proven to have metastasis. Sensitivity and specificity of US were 61.9% and
81.8%, respectively, with a positive predictive value (PPV) of 65.8% and negative predictive
value (NPV) of 79.2%. Sensitivity and specificity of US-guided FNAB were
86.9% and 100%, respectively, with a PPV of 100% and a NPV of 71.7%.
Conclusion: US and US-guided FNAB performed for axillary staging are useful
methods with a high specificity and positive predictive value in invasive breast cancer
patients |
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Keyword : Breast neoplasm; Ultrasound(US); Axilla; Lymph nodes; Fine needle aspiration |
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pdf파일 : 281-286장미정.pdf
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