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| Comparison of the Usefulness of four Risk-of-Malignancy
Indices using Ultrasonography in Ovarian masses |
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| Moo Sung Jo, MD Su Hyun Moon, MD, Jong Kil Joo, MD, Dong Soo Suh, MD,
Ki Hyung Kim, MD, Man Soo Yoon, MD |
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| 1Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, Korea |
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| Purpose: The aim of this study was to evaluate the usefulness of four Risk-of-
Malignancy Indices (RMI) in women with ovarian masses.
Materials and Methods: Between January 2007 and December 2008, 344 women
who visited our hospital for surgical exploration due to an ovarian mass were enrolled
in this study. Each RMI was based on the combination of menopausal status, ultrasound
findings of ovarian masses, and absolute level of serum CA-125. A cutoff level
of 200 was chosen as the threshold for determining between malignant and benign
ovarian masses in RMI 1, RMI 2, and RMI 3. A cutoff level of 450 was chosen as the
threshold in RMI 4. Sensitivity, specificity, positive predictive value (PPV), and negative
predictive value (NPV) were determined.
Results: The combination of four malignancy indices is more accurate than
menopausal status, ultrasound findings, and serum CA-125 alone, respectively for
determining whether a mass is benign or malignant. RMI 1 and RMI 4 were found to
be better than RMI 2 and RMI 3. RMI 4 was the most reliable test among them. The
relationship between RMI 1 and RMI 4 was not statistically significant. With the cutoff
level for RMI 4 at 450, the corresponding, sensitivity, specificity, positive predictive
value, and negative predictive value were 72.1%, 88.0%, 56.4%, 93.9%, respectively.
Conclusion: All four RMI were reliable tests for determining whether ovarian masses
are malignant or benign, and RMI 4 was the most reliable index among them. |
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| Keyword : Ovarian masses; Risk of malignancy index |
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pdf파일 : 157-164조무성.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2010 ; 29 (3) : p.157-164
