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| Ultrasonographic Differentiation of Small Angiomyolipoma from Renal Cell Carcinoma by Measuring Relative Echogenicity on PACS |
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| Myoung Seok Lee, MD1 Jeong Yeon Cho, MD1,2,3, Seung Hyup Kim, MD1,2,3 |
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| 1Department of Radiology, Seoul National University Hospital, 2Institute of Radiation Medicine and 3Kidney Research Institute, Seoul National University Medical Research Center |
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| Purpose: To retrospectively evaluate the diagnostic value of ultrasonographic differentiation
of small angiomyolipomas (AMLs) from renal cell carcinomas (RCCs) by
measuring relative echogenicity (RE) on PACS.
Materials and Methods: Thirty-six cases of < 3 cm, pathologically-proven RCCs
and 42 cases of size-matched AMLs were enrolled. We measured the grayscale representing
echogenicity of the mass, the renal cortex, and the sinus fat on PACS using
a ROI cursor. The RE of the tumor was calculated by setting the grayscale of the renal
cortex and sinus fat as 0% and 100%, respectively. We compared REs of AMLs and
RCCs, including subgroups of each tumor. ROC analyses between RCCs and AMLs
or non-fatty AMLs were performed for obtaining diagnostic performance (Az value) of
RE measurement and for extracting sensitivities of RE with fixed specificities of 90%
and 95%.
Results: The RE of AMLs was higher than RCCs (p < 0.05). The RE of non-fatty
AMLs was significantly lower than fatty AMLs, and higher than any subgroups of
RCCs (p < 0.05). RE measurement provided good diagnostic performance (Az ≥
0.840, p < 0.05) with competitive sensitivity/specificity for differentiating AMLs from
RCCs regardless of AML subgroups.
Conclusions: RE measurement on PACS can be helpful in the differential diagnosis
of small AMLs and RCCs with the intrinsic merits of ultrasonography. |
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| Keyword : Kidney; Angiomyolipoma; Renal cell carcinoma; PACS; Ultrasound |
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pdf파일 : 105-113이명석.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2010 ; 29 (2) : p.105-113
