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| Usefulness of High-Frequency Compound Spatial Sonography in the Assessment of Hepatitis B Virus Related Chronic Liver Disease |
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| Hyung Soo Kim, M.D. Sang Hoon Cha, M.D.*, Hwan Hoon Chung, M.D.*, Ki Yeol Lee, M.D.*, Baek Hyun Kim, M.D.*, Kyung Ah Kim, M.D.*, Yoon Hwan Kim, M.D.*, Cheol Min Park, M.D.*, Eung Seok Lee, M.D.**, Kwan Soo Byun, M.D.*** |
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| Department of Radiology, Wonkwang University College of Medicine *Department of Radiology, Korea University College of Medicine **Department of Pathology, Korea University College of Medicine***Department of Internal Medicine, Korea University College of |
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| PURPOSE : To evaluate the liver parenchyma according to the echo patterns of CSS (compound spatial sonography),
and to correlate them with the extent of hepatic fibrosis and the serum aminotransferase level.
MATERIALS and METHODS : The CSS images were classified into the following three echo patterns: type I, a normallooking
echo; type II, hyperechoic or hypoechoic nodules scattered in a normal-looking echo; type III, a severely
heterogeneous echogenic or hypoechoic honeycomb-like echo. The CSS findings were correlated with the
histopathology findings in 63 patients with HBV. The serum aminotransferase levels and the occurrence of acute
exacerbation in 168 patients with HBV, with and without a progressed parenchymal echo pattern, and who
were followed up more than 1-year period, were compared. The interobserver agreement between the two radiologists
for assessing the parenchymal echo pattern was scored.
RESULTS : The correlation between the CSS pattern and hepatic fibrosis was statistically significant (correlation coefficient
= 0.58, p < 0.05). The baseline serum aminotransferase level was not significantly different between the
patients with and without a progressed parenchymal echo pattern. However, the rate of acute exacerbation was
higher in patients with a progressed parenchymal echo pattern (p < 0.05). The interobserver agreement was
good (k statistic = 0.63, 0.78).
CONCLUSION : The liver parenchymal pattern based on the 5-12 MHz CSS is a useful and objective tool for diagnosing
and monitoring HBV related chronic liver disease. |
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| Keyword : Liver, fibrosis Liver, US Ultrasound (US), utilization Hepatitis |
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pdf파일 : 13-19김형수.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2007 ; 26 (1) : p.13-19
