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| Usefulness of the Hepatic Vein Transit Time Measured by Contrast-enhanced Gray-scale Harmonic Imaging in the Differentiation of Liver Cirrhosis and Chronic Hepatitis |
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| Na Mi Choi, M.D. Won Jae Lee, M.D. Hyo Keun Lim, M.D. Jae Hoon Lim, M.D. |
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| *Department of Diagnostic Radiology and Center for Imaging Science, Samsung Medical Center,Sungkyunkwan University School of Medicine |
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| PURPOSE : To evaluate the usefulness of the hepatic vein transit time (HVTT) obtained by contrast-enhanced gray-scale
harmonic imaging for the detection of liver cirrhosis (LC) in patients with chronic hepatitis (CH).
MATERIALS and METHODS : Over a recent 8-month period, 31 patients with pathologically proven chronic hepatitis
and liver cirrhosis (n=8) or chronic hepatitis alone (n=23) were prospectively examined using contrast-enhanced
pulse inversion harmonic imaging (HDI 5000: Philips, Bothell, Wash). The HVTT was defined as the
time interval from the initiation of an intravenous bolus injection of a microbubble contrast agent to the arrival
time of the first echogenic bubbles in the hepatic vein. The HVTTs of the LC and CH groups were compared.
Also, the diagnostic value of different values or ranges of HVTT for the detection of LC was assessed.
RESULTS : The HVTT of the patients with LC (range, 11-22 seconds; mean, 16.1±3.8 seconds) was significantly
shorter than that of the patients with CH (range, 13-35 seconds; mean, 22.7±5.8 seconds) (p < .001). An
HVTT of 22-24 seconds showed a sensitivity of 100%, but poor specificity (39-52%) and a poor positive predictive
value (32-45%) for the detection of LC. In the range of HVTT from 18 to 24 seconds, 19 seconds
seemed to provide the best predictive value for the detection of LC.
CONCLUSION : HVTT appears to be useful for the detection of LC in patients with CH, however further study is
needed, in order to improve on the limited diagnostic value of our results. |
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| Keyword : Liver cirrhosis Ultrasound (US), contrast media |
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pdf파일 : 127-132 최나미.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2004 ; 23 (3) : p.127-132
