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Usefulness of Intracavitary Urokinase Injection under Sonographic Guidance in Treatment for Periappendiceal Abscess |
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Jong Soo Ha, M.D. Sang Hoon Cha, M.D., Bo-Kyoung Seo, M.D.*, Baek Hyun Kim, M.D., Hwan Hoon Jung, M.D., Taik-Kun Kim, M.D., Cheol Min Park, M.D.** , Kyoo Byung Chung, M.D.* |
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Department of Diagnostic Radiology, Ansan Hospital School of Medicine, Korea University *Department of Diagnostic Radiology Anam Hospital **Department of Diagnostic Radiology Guro Hospital |
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PURPOSE : To evaluate usefulness of intracavitary urokinase injection for the treatment of small sized
periappendiceal abscess which was not unsuitable for percutaneous catheter drainage.
MATERIALS and METHODS : From December 1997 to December 1999, we performed intracavitary injection of
urokinase as a treatment of periappendiceal abscess in six patients. Initially, aspiration of the abscess was
done using a 18 G needle under sonographic guidance. We measured the maximal length of residual abscess
and injected 5000 IU of urokinase per centimeter of the diameter of the residual abscess. 24 hours after the
injection of urokinase, repeated aspiration of the residual abscess was done, and follow-up sonographic
examination was performed.
RESULTS : The size of initial abscesses in each patients was ranged from 1.6×1.2 to 5.8×3.4 cm (mean = 3.9
×2.4 cm), and initial volume of aspirated pus was ranged from 3 to 31 cc (mean = 11.8 cc). 24 hours after
the injection of urokinase, the volume of reaspirated pus was ranged from 4 to 13.5 cc (mean = 10.4 cc).
Follow-up sonography performed 3 to 10 days later revealed no residual abscess. The mean duration of
hospitalization was 5.5 days.
CONCLUSION : Intracavitary urokinase injection under the sonographic guidance can be a useful method for the
treatment of small sized periappendiceal abscess which is not suitable for percutaneous catheter drainage. |
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Keyword : Appendix US Appendicitis Urokinase |
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pdf파일 : 289-294하종수.pdf
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