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| Safety and Effectiveness of Percutaneous Biopsy of Focal Splenic Lesions under Ultrasonographic Guidance |
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| Hyun Young Han, M.D. Joo Heon Kim, M.D.*, Kyung Sook Shin, M.D.** |
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| Department of Diagnostic Radiology, Eulji University School of Medicine, *Department of Anatomical Pathology, Eulji University School of Medicine, **Department of Diagnostic Radiology, Chungnam National University |
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| PURPOSE : To evaluate the diagnostic yield and safety of ultrasound (US)-guided percutaneous needle biopsy for the
diagnosis of focal splenic lesions.
MATERIALS and METHODS : US guided, automated needle biopsy using an 18-gauge cutting needle was performed in
11 patients, consisted of nine men and two women (mean age = 49 years), with focal splenic lesions detected on
the CT or US. Six patients (55%) had multiple lesions while five (45%) had a single lesion. Two of eleven patients
had splenomegaly. None of 11 patients had the prior diagnosis of extrasplenic or hematopoietic malignancies.
The biopsy was considered successful if a specific pathological diagnosis was possible. The diagnostic
yield and frequency of complication were retrospectively analysed
RESULTS : Tissue adequate for histological diagnosis was obtained in nine (82%) of 11 patients, and no complications
other than mild, localized discomfort occurred. Multifocal splenic lesions without splenomegaly in five patients
were confirmed as Hodgkin’s disease (n=2), tuberculosis (n=1), infarction (n=1), and hemangioma (n=1).
All single lesion in four patients were proven as benign conditions including hamartoma (n=2), lymphangioma
(n=1) and chronic organizing abscess (n=1), and only one of them with a large hamartoma received splenectomy
while others did not receive further treatment. Although in two (18%) patients with multiple lesions and splenomegaly,
no specific diagnosis was established by US-guided biopsy, malignant lymphoma and Hodgkin’s
disease were confirmed by surgery.
CONCLUSION : US-guided automated needle biopsy is a safe and valuable procedure that can provides a specific diagnosis
in patients with splenic lesions. |
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| Keyword : Spleen, US Spleen, biopsy Biopsies, technology |
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pdf파일 : 091-096한현영.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2002 ; 21 (2) : p.91-96
