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| Hyperdynamic Circulatory Changes in Liver Cirrhosis: Comparative Evaluation by Doppler Ultrasonagraphy with Normal Subjects |
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| Dae Wook Im Dae Wook Im, M.D., Soon Koo Baik, M.D., Jung In Suh, M.D., Jae Woo Kim, M.D., Yong Soon Park, M.D., Hyun Soo Kim, M.D., Dong Ki Lee, M.D., Sang Ok Kwo |
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| Department of Internal Medicine, Yonsei University, Wonju College of Medicine |
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| PURPOSE : To evaluate the cardiovascular and splanchnic hemodynamic changes in patients with liver cirrhosis and
to compare with those of the normal controls using Doppler ultrasonography.
MATERIALS and METHODS : A total of 129 patients including 23 of Child-Pugh class A, 24 of class B, 30 of class C,
and 52 of the control group were included. Cardiac output (CO), systemic vascular resistance index (SVRI), and
blood flow and pulsatility index (PI) of the superior mesenteric artery (SMA) were evaluated and compared among
each groups.
RESULTS : CO and SMA blood flow in the cirrhotic group were significantly higher than those in the control group,
and the increase in CO and SMA blood flow showed a statistically significant correlation with the degree of liver
dysfunction (p<0.01). SVRI and SMA PI reflecting vascular resistance in the cirrhoic group were significantly
lower than those in the control group, and the decrease in SVRI and SMA PI also showed a statistically significant
correlation with the degree of liver dysfunction (p<0.01). SMA blood flow showed a statistically significant
inverse relationship with SMA PI (R2=0.230) .
CONCLUSION : Hyperdynamic circulatory changes such as increases in CO and splanchnic blood flow were present
in patients with liver cirrhosis. These changes may contribute to the development and maintenance of the portal
hypertension due to an increase in portal blood flow.an increase in portal blood flow. |
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| Keyword : Liver, cirrhosis, Liver, US, US, Doppler studies |
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pdf파일 : k20200273.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2001 ; 20 (4) : p.273-277
