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| Power Doppler Ultrasound of Breast Cancer: Correlation with Histologic Microvessel Density and Lymph Node Metastasis |
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| Eun-Kyung Kim Yong Hee Lee, Hong Ju Son, Ki Keun Oh, Hyun Cheol Chung, Kyong Sik Lee |
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| Department of Diagnostic Radiology, Yonsei University College of Medicine |
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| PURPOSE : To evaluate how breast cancer vascularity detected by power Doppler sonography correlates with microvessel
density(MVD) and lymph node involvement.
MATERIALS and METHODS : Power Doppler US was performed on 47 patients with pathologically diagnosed invasive
ductal carcinoma. According to the presense or absence of vessels, power Doppler findings were categorized regarding
total tumors and tumors less than 2cm. MVD was assessed immunohistochemically using polyclonal
antisera against factor VIII. Tumor vascularity was correlated with MVD and lymph node involvement.
RESULTS : Among 47 infiltrating ductal carcinomas, 35(74.5%) cases were vascular and 12(25.5%) cases were
avascular on power Doppler US. The mean MVD of the vascular and avascular carcinomas did not show any
statistical difference. However, lymph mode involvement showed significant statistical difference between the
two groups (51.4% versus 25.0%, p=0.036), even though in cancers less than 2cm (40% versus 22.2%,
p=0.047).
CONCLUSION : Breast cancer vascularity detected by power Doppler sonography was not correlated with MVD but
correlated with lymph node involvement. So we suggest that power Doppler sonography may be useful for predicting
lymph node metastasis. |
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| Keyword : Breast neoplasms, US, Ultrasound (US), Doppler studies |
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pdf파일 : 319김은경.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2000 ; 19 (4) : p.319-323
