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| Usefulness of Transrectal Ultrasound-guided 12 Core Biopsy Method in Patients with Clinically Suspected Prostate Cancer |
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| Se Hwan Kwon M.D. Joo Won Lim M.D., Seong Jin Park M.D.,Young Tae Ko M.D., Yoon Wha Kim M.D. |
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| Department of Diagnostic Radiology, Kyung Hee University Hospital, Deartment of Pathology, Kyung Hee University Hospital |
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| PURPOSE : To evaluate the improvement of prostate cancer detection provided by transrectal ultrasound(TRUS)-guided
12 core biopsy method compared with sextant biopsy method.
MATERIALS and METHODS : Between June 1997 and February 1999, 29 patients with pathologically proven prostate
cancer in 124 patients who underwent TRUS-guided 12 core biopsy method were evaluated. They had abnor-mal
findings in prostate specific antigen (PSA), digital rectal examination (DRE) or TRUS findings. The
prostate was diffusely enlarged in all patients on DRE finding and In 15 cases(15/29, 52%), hard nodule was
palpated. The average of PSA and prostate specific antigen density (PSAD) is 229.33 ng/ml (1-2280) and 9.14
ng/ml/cm3 (0.048-142.5), respectively. 12 transrectal biopsy, including 2 transition zones, was performed in
both lobe. 6 biopsies were located in both base, middle and apex. Then 2 biopsies were inserted between 3 biop-sies
in both peripheral zone and 2 biopsies were performed in both transition zone. Each specimen was patho-logically
examined. The results of pathology were compared with method 1 and 2, respectively. We defined the
method 1 and 2 as different sextant biopsy method. The method 1 is that cores are taken from both base, middle
and apex and method 2 is that cores are taken from both base, apex and transition zone. TRUS findings were an-alyzed
by two radiologists.
RESULTS : Of the 29 patients with prostate cancer, 3 (10%) had carcinomas only in the additional regions as com-pared
with method 1. When compared with method 2, 2 (7.0%) had carcinomas only in the additional regions. 2
patients were same in both cases. TRUS findings were abnormal in 21 cases in all patients and 20 were patients
whose 12 biopsy method was not helpful. 12 biopsy method was helpful in 2/8 (25%) whose TRUS findings
were non-specific and 1/21 (4.8%) whose TRUS findings were abnormal. Small low echoic lesion was seen in
one patient whose 12 biopsy method was helpful, but cancer was found in other area.
CONCLUSION : TRUS-guided 12 core biopsy method may be superior to sextant biopsy method for diagnosing can-cer
of the prostate when TRUS finding is non-specific. But, sextant biopsy method is sufficient when TRUS
finding is abnormal. |
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| Keyword : Prostate, biopsy, Prostate, neoplasms, Prostate, US |
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pdf파일 : 077권세환1.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2000 ; 19 (2) : p.77-83
