|
Contrast-enhanced Power Doppler US of Hepatocellular C a rcinomas : Quantitative Analysis |
|
Ah Young Kim, M.D. Byung Ihn Choi, M.D., Tae Kyoung Kim, M.D.,Kyoung Ho Lee, M.D., Joon Koo Han, M.D. |
|
Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine |
|
Purpose : To determine peak time and duration of contrast enhancement of nodular hepatocellular carcinoma (HCC)
on contrast-enhanced power Doppler ultrasound(US) with Levovist
Ⓡ
by quantitative analysis.
Materials and Methods : Twenty eight patients with nodular HCC were prospectively evaluated with power Doppler US
by one examiner. Serial images were obtained before and after injection of 300mg/mL US contrast agent(SH U
508 A, Levovist
Ⓡ
, Schering) with the injection rate of 0.2mL/sec. Power Doppler signals on obtained digital im-ages
were quantified using ‘Ultrasound Imaging Tool Version 1.0 ’(Seoul, Korea). The grade, peak time and du-ration
of contrast enhancement of the tumors were analyzed.
Results : For nodular HCCs, mean peak enhancement time was 60 seconds after injection of Levovist
Ⓡ
(mean en-hanced
area, 41.6 ±28.6%). These tumoral enhancement decreased from 90 seconds and returned to near base-line
state at 5 minutes after injection of Levovist
Ⓡ
. Maximum enhanced areas (%) were variable at a rangeof 8-
98.5% and mean maximum enhanced area was 46.4 ±2 8 . 6 % .
Conclusion : On contrast-enhanced power Doppler US with Levovist
Ⓡ
, nodular HCCs showed peak contrast enhance-ment
(41.6 ±28.6%) at 60 seconds after injection of a contrast agent. This tumoral enhancement
nearly disappeared at 5 minutes after injection of contrast agent. |
|
Keyword : Liver neoplasms, blood supply, Ultrasound (US), contrast media , Ultrasound (US), power Doppler studies |
|
pdf파일 : 269김아영.pdf
|
|